Spillage, mildew, bed bugs, dust mites, dog chewing, and pee mishaps — they can all ruin a perfectly fine mattress. While cleaning a mattress may seem like no biggie, we assure you that it can be a daunting task. When such accidents happen, the best mattress protectors can save the day!
The best mattress protectors are usually made of soft, waterproof fabrics that prioritize comfort and protection. These protectors can be highly beneficial in saving precious time and effort, and extending the life of your comfy mattress.
Since each of us prefers different types of mattresses, one single type of protector may not be suitable for all. So, we have brought an assortment of top-rated options that can be great defenses against all kinds of mishaps. Keep reading to know more ways in which you can keep your beds protected from your four-legged baby, no matter the breed!
Can a Mattress Protector Save a Bed from Dogs?

A mattress protector can be used to protect a bed from dogs. These protectors serve to guard against messes, stains, pee accidents, and dog chewing. They are waterproof and can easily be used on top of your mattress to deal with moisture.
Not only do these protectors offer exclusive protection, but they are also easy to clean. Most of these protectors are investment-safe and can help prevent the everyday wear and tear of your expensive mattress. Make sure you choose a protector with soft fabric like cotton, which doesn’t interfere with your mattress’ superior quality. Washing them regularly is an economical option to help keep your bed in good condition.
The Best Mattress Protectors to Buy in 2025
Accidents cannot be avoided, but they can be prevented with the best mattress protectors. Here are our top picks that can make all the difference in your life!
BEST OVERALL
SafeRest Premium Mattress Protector

PHOTO CREDIT: AMAZON
Why We Love
Soft, smooth fabric
Machine washable
Waterproof membrane
Keeps the mattress dry
Vinyl, phthalates, and PVC-free
But…
May be short on the sides
A premium choice for you and your family—SafeRest mattress protectors are popular for their comprehensive protection against urine, fluids, dust mites, and allergens, which makes them a great choice for homes with kids, pets, and people with allergies. If you are fretting about your dog’s pee stains, then this mattress protector can be your go-to option!
SafeRest mattress protectors are made of superior-quality cotton terry, which is designed to absorb fluids and enable breathability. It doesn’t create any sound and is suitable for light sleepers.
MOST VERSATILE
Be Decor Cotton Terry Mattress Protector

PHOTO CREDIT: AMAZON
Why We Love
Tear-resistant
Waterproof
Soft and comfy
No crinkling sound
Hassle-free maintenance
Offers comprehensive protection
But…
Some may find it too thin
The Be Decor Cotton Terry Mattress Protector is a multifunctional protector that can add a touch of luxury to your bedroom. It boasts a luxurious cotton-terry surface that adds to your sleeping comfort while offering a good deal of protection to your mattress. Earning the title of “versatile protector”, it can be used both as a bedsheet and a protector.
It also stands out as one of the best protectors against fluids. Be it your pet’s pee or your toddler’s bed-wetting, this protector will not disappoint you. It is available in a variety of sizes, so you can find a snug fit for any bed size.
BEST PET-FRIENDLY
TASTELIFE Queen Mattress Protector

PHOTO CREDIT: AMAZON
Why We Love
OEKO-TEX certified
Deep-pocket fitted
Waterproof TPU backing
Assures edge-to-edge fit
Features Invisible-Shield for comfort
Free of PVC, phthalates, or fire-retardant treatments.
But…
Not durable enough
The TASTELIFE Queen Mattress Protector is one of our top picks because it checks all the boxes of a good protector and ensures an outstanding sleeping experience. Featuring “Naked-Sleep Degree of Super Soft,” the brand offers a premium-quality microfiber terry cover that is breathable, skin-friendly, and helps regulate body temperature.
Nobody likes an ill-fitted mattress, and so this queen-size protector, with a standard size of 60 by 80 inches, snugly fits like a premium bedsheet. The protector contains no toxic chemicals, such as benzene or vinyl, and can be safe for use with pets and kids. Cleaning this protector can be a breeze as it is machine wash-safe. Use it to protect your mattress against dog urine and fluids, and enjoy life, King Size!
BEST FOR ALLERGIES
LINENSPA Premium Mattress Protector

PHOTO CREDIT: AMAZON
Why We Love
Secure and quiet
Easy maintenance
Breathable fabric
Smooth top design
Prevents leaks effectively
But…
Not the best against pet hair
If you are looking for a solution to dust mites and allergens on your mattress, then look no further than the LINENSPA Premium Mattress Protector! It combines comfort with protection and provides hypoallergenic protection against mites and allergens. Featuring a top surface made of pure polyester and a backing of polyurethane, the protector excels at extending the life of your mattress.
The brand claims that it is 100% waterproof because of its AquaTight barrier and is suitable for homes with toddlers and pets. This protector can be used on mattresses up to 14 inches thick, as it comes in a fitted-sheet style with elasticized corners that simplify the bed-making process. Cleaning it is no sweat at all, as it is machine-washable!
Best for 360° Protection
Kayfia Mattress Protector

PHOTO CREDIT: AMAZON
Why We Love
Skin-friendly
Easy to clean
No vinyl content
Deep-pocket band
Super comfortable and quiet
But…
Not very durable
You can now cuddle and sleep with your pet without being anxious about pee mishaps, as we have a real-life solution in the form of the Kayfia Mattress Protector for you! Crafted with premium polyester fabric, this mattress protector is thin, soft, silky, and breathable. The fabric is known for its ability to stay dry while regulating heat.
It can be a good fit for all parents and pet owners, as the mattress uses TPU fabric at the back, which is absolutely waterproof and safe against fluids. Designed for every mattress with a thickness of 6–15 inches, it boasts its 360° full surround feature and elastic band skirt style that prevents shifting and keeps it in place.
BEST FOR STAINS
Inspire Waterproof Mattress Protector

PHOTO CREDIT: AMAZON
Why We Love
Lightweight
Machine wash safe
Has a dry touch top layer
Absorbs and traps fluids
Offers ultimate coverage
But…
Doesn’t have a grip surface
Messy stains created by your toddler or pet can be awfully difficult to remove, and there is no guarantee that they will be gone forever. To tackle these issues, our editor recommends this dark navy-colored mattress protector from the Inspire Store. The dark color helps conceal stains, and its latex-free material can resist everyday wear and tear, along with fluids. Its waterproof design excels at protecting sheets and beds from getting wet and provides coverage against moisture.
Ideal for overnight use, this soft mattress protector can help you ease into sleep and forget the world while sleeping comfortably. The protector is low maintenance and super easy to remove and clean. Being reusable, it can stand out as an eco-friendly mattress protector.
BEST FOR UNTRAINED DOGS
SureGuard Mattress Protector

PHOTO CREDIT: AMAZON
Why We Love
Soft fabric
Noiseless
Easy to clean
Has a hypoallergenic backing
Compatible with all types of mattresses
Equipped with a thin, lightweight mattress pad
But…
Does not fit snugly
If you have an untrained dog at home, then potty training accidents are bound to happen. In such cases, SureGuard Mattress Protectors can assist you in keeping your bed mess-free without compromising on your comfort. The breathable mattress is made of a 100% cotton terry top, meant to absorb fluids and moisture while keeping the temperature regulated.
This washable mattress offers top protection against liquids, bed-wetting, and mess stains, thus prolonging the life of your mattress. Boasting its ability to shield against dirt, dust, allergens, mites, and dander, along with fluids, the brand offers a 10-year quality guarantee. The fabric is free from harmful chemicals like PVC, Phthalates, and vinyl, which makes it safe for pets and kids.
How We Chose the Best Mattress Protectors?
Our curation contains the best mattress protectors that can serve as a defense against toddler leaks, pet urine, dog, chewing, and mess stains. This list has been curated after consulting industry experts and dog owners who have shared their real-life experiences with us. The listed products are popular for their durability, performance, functionality, and ease of maintenance. Pick your favorite and be ready to enjoy a clean mattress for a good night’s sleep!
FAQ
What is the best mattress protector for dog urine?
SafeRest Premium Mattress Protector and BE DECOR Cotton Terry Mattress Protector are the best mattress protectors for dog urine. Not just dog urine, but they can protect against all fluids and allergens. The fabrics used by these mattress protectors are soft, smooth, and comfortable, along with being waterproof.
What kind of mattress protector is best?
Waterproof mattress protectors that keep the mattress dry are the best. The softness and comfort of these protectors go hand in hand. The best mattress protectors are noiseless, non-toxic, and durable too.
How to protect a bed from dogs?
Using a mattress protector can help protect a bed from dogs. Such protectors are fluid-proof and chew-resistant, which makes them great for homes with dogs.
What removes dog urine smell from a mattress?
Cleaning a mattress protector can help you get rid of the dog urine smell. Using a pet odor eliminator, too, can help remove dog urine smell from the mattress.
Are expensive mattress protectors worth it?
If an expensive mattress protector helps with protection, comfort, and thermal regulation, then such protectors are worth it. These are some of the important features of a mattress protector that can add to the life of your mattress and value to your life!
What can I use to stop my dog from peeing on my bed?
The basic way to stop your dog from peeing on your bed is to either train them or prevent access to the bed. But keeping them away is probably not possible (we know how much you love them!), so get a superior-quality mattress protector that can retain fluids like dog pee and prevent your bed from being affected.