(Learn more about mucopolysaccharidoses in dogs. Picture credit: DusanManic / Getty Images)

Mucopolysaccharidoses in Dogs: Symptoms, Causes, & Treatments

Mucopolysaccharidoses in dogs is a rare genetic condition. The condition can affect a dog’s organs and cause physical deformities.

Specifically, the condition happens when a substance called glycosaminoglycans (GAG) builds up in a dog’s tissues. This is due to a dog not having enough lysosomal enzymes.

Unfortunately, certain dog breeds can be predisposed to the condition, including Labrador Retrievers, Plott Hounds, and German Shepherds. Also, there is no current cure for the condition.

Technically, the condition is also known as metabolic disorders due to lysosomal enzyme deficiency in dogs.

If you see the signs of the condition in your dog, then get to a veterinarian for a proper diagnosis and treatment.

Here’s what you should know about the symptoms, causes, and treatments for the condition.

Symptoms of Mucopolysaccharidoses in Dogs

The condition produces a number of symptoms. For example, some of the most common symptoms include:

  • Bone diseases
  • Enlarged tongue
  • Cloudy eyes
  • Dwarfism
  • Bigger than normal head size
  • Congestive heart failure
  • Joint problems
  • Leg problems
  • Slow growth

Causes of Mucopolysaccharidoses in Dogs

(Picture credit: FatCamera / Getty Images)

The cause of the condition is genetic. This means that a dog is born with the condition.

Additionally, certain dog breeds are predisposed to the condition. For example, some of those breeds include:

  • German Shepherds
  • Labrador Retrievers
  • Miniature Pinschers
  • Plott Hounds
  • Welsh Corgis
  • Rottweilers
  • Miniature Poodles
  • Brazilian Terriers
  • Boston Terriers
  • Miniature Schnauzers

Treatments for Mucopolysaccharidoses in Dogs

Firstly, your vet will ask about your dog’s symptoms. Secondly, your vet will ask about your dog’s full medical history. This will include breed-specific problems.

Thirdly, your vet will carry out a full physical examination. Blood and urine tests will be taken. Ultimately, the condition is diagnosed by measuring the amount of lysosomal enzymes in your dog’s blood. X-rays can also be used to examine any bone-related issues.

Technically, there is no current cure for the condition. Although bone marrow transplants can help, as long as your dog is at a young enough age. Your vet can help advise on whether this procedure will be an option.

Additionally, enzyme replacement therapy can be considered. Although this is a costly process.

Finally, you can read more about more general lysosomal-based problems for dogs here.

Have you ever cared for a dog who suffered from this condition? How did your vet help your dog recover? Let us know in the comments section below.

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